The commonest RP stationary phases are determined by a silica help, that is area-modified by bonding RMe2SiCl, wherever R can be a straight chain alkyl group for instance C18H37 or C8H17.By decreasing the pH on the solvent in a cation Trade column, For illustration, extra hydrogen ions are available to compete for positions on the anionic stationar
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Insert a known level of the antidepressant protriptyline, which serves being an inside normal, to each serum sample and to every external common. To get rid of matrix interferents, pass a 0.five-mL aliquot of each serum sample or conventional through a C18 solid-section extraction cartridge. Right after washing the cartridge to remove the interfere
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